The route follows long stretches on the water channels and irrigation systems along the Po River.
The valley is broadly divided into an upper, drier part, often not particularly suited for agriculture, and a lower, very fertile, and well-irrigated section
Surface runoff water (the Po and its affluents) is not of much value to the valley’s dense population for drinking and other immediate uses, being unreliable, often destructive, and heavily polluted by sewage and fertilizers. Its main anthropic value is for hydro-electric power, irrigation, and industrial transport. The cost of purifying it for human consumption makes that process less feasible. The fresh drinking water comes from hundreds of thousands of wells.
The bassa Padana was settled and farmed earliest, in Etruscan and Roman times. After the collapse of the Roman Empire (5th century AD), lack of maintenance of the irrigation systems associated with a cooling climate phase (i.e. the so-called Migration Period or The Dark Age Cold Period) led to the progressive waterlogging of the Po Valley and the natural depressions on the right side of the Po turned in vast swamp basins. The waterlogging process of the area continued until the 10th-century influencing the human sustenance and settling practices. According to historical-archaeological data, indeed, the wetlands were exploited for fishing as well as for transport by boat while the early medieval sites settled on the fluvial ridges, in topographically higher and strategic position in the surrounding swampy meadows.
The Po Valley has been completely turned to agriculture since the Middle Ages, when efforts from monastic orders, feudal lords and free communes converged. The older and smaller cities deriving from ancient times are still located there.
According to historical maps and documents the land reclamation of the Po Valley reached its peak during the Renaissance (15th–16th centuries) and continued in the Modern Age (17th–18th centuries), with the last marsh areas only being reclaimed in the 20th century: channels and drainage system are still active and allow the Po Valley to be drained and be cultivatable.





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